@article {4300,
	title = {Glia instruct developmental neuronal remodeling through TGF-β signaling.},
	journal = {Nature Neuroscience},
	volume = {14},
	year = {2011},
	month = {2011 Jun 19},
	pages = {821-3},
	abstract = {<p>We found that glia secrete myoglianin, a TGF-β ligand, to instruct developmental neural remodeling in Drosophila. Glial myoglianin upregulated neuronal expression of an ecdysone nuclear receptor that triggered neurite remodeling following the late-larval ecdysone peak. Thus glia orchestrate developmental neural remodeling not only by engulfment of unwanted neurites but also by enabling neuron remodeling.</p>
},
	keywords = {Animals, Developmental, Double-Stranded, Drosophila, Drosophila Proteins, Gene Expression Regulation, Genetically Modified, Green Fluorescent Proteins, MicroRNAs, Models, Mushroom Bodies, Mutation, Neurogenesis, Neuroglia, Neurological, RNA, Signal Transduction, Transforming Growth Factor beta},
	issn = {1546-1726},
	doi = {10.1038/nn.2833},
	author = {Awasaki, Takeshi and Huang, Yaling and O{\textquoteright}Connor, Michael B and Lee, Tzumin}
}
