@article {1099,
	title = {Ester bonds in prodrugs.},
	journal = {ACS Chemical Biology},
	volume = {3},
	year = {2008},
	month = {2008 Apr 18},
	pages = {203-6},
	abstract = {<p>A recent study challenges the oft-held notion that ester bonds in prodrug molecules are cleaved rapidly and completely inside cells by endogenous, nonspecific esterases. Structure-activity relationship studies on acylated sugars reveal that regioisomeric compounds display disparate biological activity, suggesting that ester bonds can persist in a cellular context.</p>
},
	keywords = {Esters, Prodrugs, Structure-Activity Relationship},
	issn = {1554-8937},
	doi = {10.1021/cb800065s},
	author = {Lavis, Luke D}
}
