@article {2364,
	title = {Olfactory coding with all-or-nothing glomeruli.},
	journal = {Journal of Neurophysiology},
	volume = {98},
	year = {2007},
	month = {2007 Dec},
	pages = {3134-42},
	abstract = {<p>We present a model for olfactory coding based on spatial representation of glomerular responses. In this model distinct odorants activate specific subsets of glomeruli, dependent on the odorant{\textquoteright}s chemical identity and concentration. The glomerular response specificities are understood statistically, based on experimentally measured distributions of activation thresholds. A simple version of the model, in which glomerular responses are binary (the all-or-nothing model), allows us to account quantitatively for the following results of human/rodent olfactory psychophysics: 1) just noticeable differences in the perceived concentration of a single odor (Weber ratios) are as low as dC/C approximately 0.04; 2) the number of simultaneously perceived odors can be as high as 12; and 3) extensive lesions of the olfactory bulb do not lead to significant changes in detection or discrimination thresholds. We conclude that a combinatorial code based on a binary glomerular response is sufficient to account for several important features of the discrimination capacity of the mammalian olfactory system.</p>
},
	keywords = {Algorithms, Animals, Discrimination (Psychology), Mice, Models, Neurological, Odors, Olfactory Bulb, Olfactory Pathways, Olfactory Receptor Neurons, Psychomotor Performance, Psychophysics, Rats, Smell},
	issn = {0022-3077},
	doi = {10.1523/JNEUROSCI.3613-08.2008},
	author = {Koulakov, Alexei and Gelperin, Alan and Rinberg, Dmitry}
}
