@article {1737,
	title = {A dynamic coupling model for sum frequency chiral response from liquids composed of molecules with a chiral side chain and an achiral chromophore.},
	journal = {Journal of the American Chemical Society},
	volume = {127},
	year = {2005},
	month = {2005 Sep 21},
	pages = {12933-42},
	abstract = {<p>A theoretical formulation for optically active sum frequency generation (OA-SFG) from isotropic chiral solutions was proposed for molecules with a chiral side chain and an intrinsically achiral chromophore. Adapting an electron correlation model first proposed by H{\"o}hn and Weigang for linear optical activity, we presented a dynamic coupling model for OA-SFG near the electronic resonance of the achiral chromophore. As a demonstration, we used this model to explain the observed OA-SFG spectra of a series of amino acids near the electronic resonance of the intrinsically achiral carboxyl group. Our model shows that the nonlinear chiroptical response comes about by the through-space correlative electronic interactions between the chiral side chain and the achiral chromophore, and its magnitude is determined by the position and orientation of the bonds that make up the chiral side chain. Using the bond polarizability values in the literature and the conformations of amino acids obtained from calculation, we were able to reproduce the relative OA-SFG strength from a series of amino acids.</p>
},
	keywords = {Amino Acids, Chemical, Infrared, Models, Spectrophotometry, Thermodynamics},
	issn = {0002-7863},
	doi = {10.1021/ja052715d},
	author = {Ji, Na and Shen, Yuen-Ron}
}
