@article {5904,
	title = {Morphological and physiological features of a set of spinal substantia gelatinosa neurons defined by green fluorescent protein expression.},
	journal = {The Journal of Neuroscience},
	volume = {24},
	year = {2004},
	month = {2004 Jan 28},
	pages = {836-42},
	abstract = {<p>The spinal substantia gelatinosa (SG) is known to be involved in the manipulation of nociceptive and thermal primary afferent input; however, the interrelationships of its neuronal components are poorly understood. As a step toward expanding understanding, we took a relatively unique approach by concentrating on a set of SG neurons selectively labeled by green fluorescent protein (GFP) in a transgenic mouse. These GFP-expressing SG neurons prove to have homogenous morphological and electrophysiological properties, are systematically spaced in the SG, contain GABA, receive C-fiber primary afferent input, and upregulate c-Fos protein in response to noxious stimuli. Together, the properties established for these GFP-labeled neurons are consistent with a modular SG organization in which afferent activity related to nociception or other C-fiber signaling are subject to integration/modulation by repeating, similar circuits of neurons.</p>
},
	keywords = {Animals, Biological Markers, Electrophysiology, gamma-Aminobutyric Acid, Ganglia, Green Fluorescent Proteins, Luminescent Proteins, Lysine, Mice, Nerve Fibers, Neurons, Pain Measurement, Patch-Clamp Techniques, Proto-Oncogene Proteins c-fos, Spinal, Substantia Gelatinosa, Transgenic, Unmyelinated},
	issn = {1529-2401},
	doi = {10.1523/JNEUROSCI.4221-03.2004},
	author = {Hantman, Adam W and van den Pol, Anthony N and Perl, Edward R}
}
