@article {45041,
	title = {Whole-cell patch-clamp recordings in freely moving animals.},
	journal = {Methods in Molecular Biology},
	volume = {1183},
	year = {2014},
	month = {2014 Jun 20},
	pages = {263-76},
	abstract = {<p>The patch-clamp technique and the whole-cell measurements derived from it have greatly advanced our understanding of the coding properties of individual neurons by allowing for a detailed analysis of their excitatory/inhibitory synaptic inputs, intrinsic electrical properties, and morphology. Because such measurements require a high level of mechanical stability they have for a long time been limited to in vitro and anesthetized preparations. Recently, however, a considerable amount of effort has been devoted to extending these techniques to awake restrained/head-fixed preparations allowing for the study of the input-output functions of neurons during behavior. In this chapter we describe a technique extending patch-clamp recordings to awake animals free to explore their environments.</p>
},
	issn = {1940-6029},
	doi = {10.1007/978-1-4939-1096-0_17},
	author = {Lee, Albert K and Epsztein, J{\'e}r{\^o}me and Brecht, Michael}
}
