@article {45054,
	title = {Manipulating nuclear architecture.},
	journal = {Current Opinion in Genetics \& Development},
	volume = {25},
	year = {2014},
	month = {2014 Apr 25},
	pages = {1-7},
	abstract = {<p>The eukaryotic genome is highly organized in the nucleus. Genes can be localized to specific nuclear compartments in a manner reflecting their activity. A plethora of recent reports has described multiple levels of chromosomal folding that can be related to gene-specific expression states. Here we discuss studies designed to probe the causal impact of genome organization on gene expression. The picture that emerges is that of a reciprocal relationship in which nuclear organization is not only shaped by gene expression states but also directly influences them.</p>
},
	issn = {1879-0380},
	doi = {10.1016/j.gde.2013.10.014},
	author = {Deng, Wulan and Blobel, Gerd A}
}
