@article {46548,
	title = {Numerical study of multi-conjugate large area wavefront correction for deep tissue microscopy.},
	journal = {Optics Express},
	volume = {23},
	year = {2015},
	month = {2015 Mar 23},
	pages = {7463-70},
	abstract = {<p>Wavefront distortion fundamentally limits the achievable imaging depth and quality in thick tissue. Wavefront correction can help restore the diffraction limited focus albeit with a small field of view (FOV), which limits its imaging applications. In this work, we numerically investigate whether the multi-conjugate configuration, originally developed for astronomical adaptive optics, may increase the correction FOV in random turbid media. The results show that the multi-conjugate configuration can significantly improve the correction area compared to the widely adopted pupil plane correction. Even in the simple case of single-conjugation, it still outperforms the pupil plane correction. This study provides a guideline for designing the optimal wavefront correction system in deep tissue imaging.</p>
},
	issn = {1094-4087},
	doi = {10.1364/OE.23.007463},
	author = {Wu, Tsai-Wei and Cui, Meng}
}
