@article {47224,
	title = {Transformation of olfactory representations in the Drosophila antennal lobe.},
	journal = {Science (New York, N.Y.)},
	volume = {303},
	year = {2004},
	month = {2004 Jan 16},
	pages = {366-70},
	abstract = {<p>Molecular genetics has revealed a precise stereotypy in the projection of primary olfactory sensory neurons onto secondary neurons. A major challenge is to understand how this mapping translates into odor responses in these second-order neurons. We investigated this question in Drosophila using whole-cell recordings in vivo. We observe that monomolecular odors generally elicit responses in large ensembles of antennal lobe neurons. Comparison of odor-evoked activity from afferents and postsynaptic neurons in the same glomerulus revealed that second-order neurons display broader tuning and more complex responses than their primary afferents. This indicates a major transformation of odor representations, implicating lateral interactions within the antennal lobe.</p>
},
	keywords = {Action Potentials, Animals, Drosophila, Excitatory Postsynaptic Potentials, GABA Antagonists, GABA-A Receptor Antagonists, Nervous System Physiological Phenomena, Neural Inhibition, Neurons, Afferent, Odors, Olfactory Pathways, Olfactory Receptor Neurons, Patch-Clamp Techniques, Picrotoxin, Receptors, GABA-A, Sense Organs, Smell, Synapses},
	issn = {1095-9203},
	doi = {10.1126/science.1090782},
	author = {Wilson, Rachel I and Turner, Glenn C and Laurent, Gilles}
}
