@article {48165,
	title = {Omnidirectional displacements for deformable surfaces.},
	journal = {Medical image analysis},
	volume = {17},
	year = {2013},
	month = {2013 May},
	pages = {429-41},
	abstract = {<p>Deformable surface models are often represented as triangular meshes in image segmentation applications. For a fast and easily regularized deformation onto the target object boundary, the vertices of the mesh are commonly moved along line segments (typically surface normals). However, in case of high mesh curvature, these lines may not intersect with the target boundary at all. Consequently, certain deformations cannot be achieved. We propose omnidirectional displacements for deformable surfaces (ODDS) to overcome this limitation. ODDS allow each vertex to move not only along a line segment but within the volumetric inside of a surrounding sphere, and achieve globally optimal deformations subject to local regularization constraints. However, allowing a ball-shaped instead of a linear range of motion per vertex significantly increases runtime and memory. To alleviate this drawback, we propose a hybrid approach, fastODDS, with improved runtime and reduced memory requirements. Furthermore, fastODDS can also cope with simultaneous segmentation of multiple objects. We show the theoretical benefits of ODDS with experiments on synthetic data, and evaluate ODDS and fastODDS quantitatively on clinical image data of the mandible and the hip bones. There, we assess both the global segmentation accuracy as well as local accuracy in high curvature regions, such as the tip-shaped mandibular coronoid processes and the ridge-shaped acetabular rims of the hip bones.</p>
},
	keywords = {Algorithms, Computer Simulation, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Imaging, Three-Dimensional, Models, Biological, Pattern Recognition, Automated, Reproducibility of Results, Sensitivity and Specificity},
	issn = {1361-8423},
	doi = {10.1016/j.media.2012.11.006},
	author = {Kainmueller, Dagmar and Lamecker, Hans and Heller, Markus O and Weber, Britta and Hege, Hans-Christian and Zachow, Stefan}
}
