@article {48315,
	title = {Single-molecule insights into mRNA dynamics in neurons.},
	journal = {Trends in Cell Biology},
	volume = {25},
	year = {2015},
	month = {2015 Aug},
	pages = {468-75},
	abstract = {<p>Targeting of mRNAs to neuronal dendrites and axons plays an integral role in intracellular signaling, development, and synaptic plasticity. Single-molecule imaging of mRNAs in neurons and brain tissue has led to enhanced understanding of mRNA dynamics. Here we discuss aspects of mRNA regulation as revealed by single-molecule detection, which has led to quantitative analyses of mRNA diversity, localization, transport, and translation. These exciting new discoveries propel our understanding of the life of an mRNA in a neuron and how its activity is regulated at the single-molecule level.</p>
},
	keywords = {Animals, Humans, In Situ Hybridization, Fluorescence, Intracellular Membranes, Neuronal Plasticity, Neurons, Protein Biosynthesis, RNA, Messenger, Signal Transduction},
	issn = {1879-3088},
	doi = {10.1016/j.tcb.2015.05.005},
	author = {Buxbaum, Adina R and Yoon, Young J and Singer, Robert H and Park, Hye Yoon}
}
