@article {49325,
	title = {Cryo-EM structure of the polycystin 2-l1 ion channel.},
	journal = {eLife},
	volume = {7},
	year = {2018},
	month = {2018 Jul 13},
	abstract = {<p>We report the near atomic resolution (3.3 {\r A}) of the human polycystic kidney disease 2-like 1 (polycystin 2-l1) ion channel. Encoded by PKD2L1, polycystin 2-l1 is a calcium and monovalent cation-permeant ion channel in primary cilia and plasma membranes. The related primary cilium-specific polycystin-2 protein, encoded by PKD2, shares a high degree of sequence similarity, yet has distinct permeability characteristics. Here we show that these differences are reflected in the architecture of polycystin 2-l1.</p>
},
	issn = {2050-084X},
	doi = {10.7554/eLife.36931},
	author = {Hulse, Raymond E and Li, Zongli and Huang, Rick K and Zhang, Jin and Clapham, David E}
}
