@article {65224,
	title = {Gas cluster ion beam SEM for imaging of large tissue samples with 10 nm isotropic resolution.},
	journal = {Nature Methods},
	volume = {17},
	year = {2019},
	month = {2020 Jan 01},
	pages = {68-71},
	abstract = {<p>We demonstrate gas cluster ion beam scanning electron microscopy (SEM), in which wide-area ion milling is performed on a series of thick tissue sections. This three-dimensional electron microscopy technique acquires datasets with \&lt;10 nm isotropic resolution of each section, and these can then be stitched together to span the sectioned volume. Incorporating gas cluster ion beam SEM into existing single-beam and multibeam SEM workflows should be straightforward, increasing reliability while improving z resolution by a factor of three or more.</p>
},
	issn = {1548-7105},
	doi = {10.1038/s41592-019-0641-2},
	author = {Hayworth, Kenneth J and Peale, David and Januszewski, Micha{\l} and Knott, Graham W and Lu, Zhiyuan and Xu, C Shan and Hess, Harald F}
}
