@article {67763,
	title = {An adaptive optics module for deep tissue multiphoton imaging in vivo.},
	journal = {Nature Methods},
	volume = {18},
	year = {2021},
	month = {2021 Oct 01},
	pages = {1259-1264},
	abstract = {<p>Understanding complex biological systems requires visualizing structures and processes deep within living organisms. We developed a compact adaptive optics module and incorporated it into two- and three-photon fluorescence microscopes, to measure and correct tissue-induced aberrations. We resolved synaptic structures in deep cortical and subcortical areas of the mouse brain, and demonstrated high-resolution imaging of neuronal structures and somatosensory-evoked calcium responses in the mouse spinal cord at great depths in vivo.</p>
},
	issn = {1548-7105},
	doi = {10.1038/s41592-021-01279-0},
	author = {Rodriguez, Cristina and Chen, Anderson and Rivera, Jos{\'e} A and Mohr, Manuel A and Liang, Yajie and Natan, Ryan G and Sun, Wenzhi and Milkie, Daniel E and Bifano, Thomas G and Chen, Xiaoke and Ji, Na}
}
