@article {67858,
	title = {The importance of accounting for movement when relating neuronal activity to sensory and cognitive processes.},
	journal = {Journal of Neuroscience: The Official Journal of the Society for Neuroscience},
	volume = {42},
	year = {2022},
	month = {2022 Feb 23},
	pages = {1375-1382},
	abstract = {<p>A surprising finding of recent studies in mouse is the dominance of widespread\&nbsp;movement-related\&nbsp;activity\&nbsp;throughout the brain, including in early\&nbsp;sensory\&nbsp;areas. In awake subjects, failing to\&nbsp;account\&nbsp;for\&nbsp;movement\&nbsp;risks misattributing\&nbsp;movement-related\&nbsp;activity\&nbsp;to other (e.g.,\&nbsp;sensory\&nbsp;or\&nbsp;cognitive)\&nbsp;processes. In this article, we 1) review task designs for separating task-related\&nbsp;and\&nbsp;movement-related\&nbsp;activity, 2) review three {\textquoteright}case studies{\textquoteright} in which\&nbsp;<em>not</em>\&nbsp;considering\&nbsp;movement\&nbsp;would have resulted in critically different interpretations of\&nbsp;neuronal\&nbsp;function, and 3) discuss functional couplings that may prevent us from ever fully isolating\&nbsp;sensory,\&nbsp;motor, and\&nbsp;cognitive-related\&nbsp;activity. Our main thesis is that neural signals\&nbsp;related\&nbsp;to\&nbsp;movement\&nbsp;are ubiquitous, and therefore ought to be considered first and foremost when attempting to correlate\&nbsp;neuronal\&nbsp;activity\&nbsp;with task-related\&nbsp;processes.</p>
},
	doi = {10.1523/JNEUROSCI.1919-21.2021},
	author = {Edward Zagha and Jeffrey C Erlich and Soohyun Lee and Gyorgy Lur and Daniel H O{\textquoteright}Connor and Nicholas A Steinmetz and Carsen Stringer and Hongdian Yang}
}
