@article {1107,
	title = {Stereochemically general approach to adjacent bis(tetrahydrofuran) cores of annonaceous acetogenins.},
	journal = {Organic Letters},
	volume = {8},
	year = {2006},
	month = {2006 Nov 23},
	pages = {5637-40},
	abstract = {<p>A series of six 2,5-disubstituted adjacent bis(tetrahydrofuran) stereoisomers with trans/erythro/cis, trans/threo/trans, or cis/threo/cis relative stereochemistry have been synthesized from known dihydroxycyclooctenes via ring opening/cross metathesis and Pd(0)-mediated asymmetric double cycloetherification. The stereochemistry of four of these isomers has been found in the biologically active annonaceous acetogenin natural products. [reaction: see text].</p>
},
	keywords = {Acetogenins, Annonaceae, Cyclization, Dioxanes, Ethers, Fatty Alcohols, Furans, Lactones, Magnetic Resonance Spectroscopy, Palladium, Solvents, Stereoisomerism},
	issn = {1523-7060},
	doi = {10.1021/ol062390l},
	author = {Wysocki, Laura M and Dodge, Matthew W and Voight, Eric A and Burke, Steven D}
}
