@article {1156,
	title = {The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila.},
	journal = {Cell},
	volume = {66},
	year = {1991},
	month = {1991 Sep 6},
	pages = {935-48},
	abstract = {<p>The maleless (mle) gene is one of four known regulatory loci required for increased transcription (dosage compensation) of X-linked genes in D. melanogaster males. A predicted mle protein (MLE) contains seven short segments that define a superfamily of known and putative RNA and DNA helicases. MLE, while present in the nuclei of both male and female cells, differs in its association with polytene X chromosomes in the two sexes. MLE is associated with hundreds of discrete sites along the length of the X chromosome in males and not in females. The predominant localization of MLE to the X chromosome in males makes it a strong candidate to be a direct regulator of dosage compensation.</p>
},
	issn = {0092-8674},
	author = {Baker, B.S. and Kuroda, M.I. and Kreber, M.J. and Ganetzky, B.}
}
