@article {981,
	title = {The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family.},
	journal = {Cell},
	volume = {29},
	year = {1982},
	month = {1982 Jul},
	pages = {995-1004},
	abstract = {<p>We have shown previously that four of five white mutant alleles arising in P-M dysgenic hybrids result from the insertion of strongly homologous DNA sequence elements. We have named these P elements. We report that P elements are present in 30-50 copies per haploid genome in all P strains examined and apparently are missing entirely from all M strains examined, with one exception. Furthermore, members of the P family apparently transpose frequently in P-M dysgenic hybrids; chromosomes descendant from P-M dysgenic hybrids frequently show newly acquired P elements. Finally, the strain-specific breakpoint hotspots for the rearrangement of the pi 2 P X chromosome occurring in P-M dysgenic hybrids are apparently sites of residence of P elements. These observations strongly support the P factor hypothesis for the mechanistic basis of P-M hybrid dysgenesis.</p>
},
	keywords = {Base Sequence, Biological Evolution, DNA Transposable Elements, Drosophila, Female, Gene Expression Regulation, Genetic, Hybridization, Infertility, Male, Nucleic Acid, Recombination, Repetitive Sequences},
	issn = {0092-8674},
	doi = {10.1186/gb-2007-8-7-r145},
	author = {Bingham, P M and Kidwell, M G and Rubin, G M}
}
@article {982,
	title = {Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method.},
	journal = {Cell},
	volume = {25},
	year = {1981},
	month = {1981 Sep},
	pages = {693-704},
	abstract = {<p>We describe the isolation of a cloned DNA segment carrying unique sequences from the white locus of Drosophila melanogaster. Sequences within the cloned segment are shown to hybridize in situ to the white locus region on the polytene chromosomes of both wild-type strains and strains carrying chromosomal rearrangements whose breakpoints bracket the white locus. We further show that two small deficiency mutations, deleting white locus genetic elements but not those of complementation groups contiguous to white, delete the genomic sequences corresponding to a portion of the cloned segment. The strategy we have employed to isolate this cloned segment exploits the existence of an allele at the white locus containing a copy of a previously cloned transposable, reiterated DNA sequence element. We describe a simple, rapid method for retrieving cloned segments carrying a copy of the transposable element together with contiguous sequences corresponding to this allele. The strategy described is potentially general and we discuss its application to the cloning of the DNA sequences of other genes in Drosophila, including those identified only by genetic analysis and for which no RNA product is known.</p>
},
	keywords = {Animals, Bacteriophage lambda, Chromosome Mapping, Cloning, DNA Transposable Elements, Drosophila melanogaster, Genes, Genetic Linkage, Molecular, Nucleic Acid, Nucleic Acid Hybridization, Repetitive Sequences},
	issn = {0092-8674},
	doi = {10.1186/gb-2007-8-7-r145},
	author = {Bingham, P M and Levis, R and Rubin, G M}
}
