@article {46929,
	title = {Inferring transient particle transport dynamics in live cells.},
	journal = {Nature Methods},
	volume = {12},
	year = {2015},
	month = {2015 Jul 20},
	pages = {838-40},
	abstract = {<p>Live-cell imaging and particle tracking provide rich information on mechanisms of intracellular transport. However, trajectory analysis procedures to infer complex transport dynamics involving stochastic switching between active transport and diffusive motion are lacking. We applied Bayesian model selection to hidden Markov modeling to infer transient transport states from trajectories of mRNA-protein complexes in live mouse hippocampal neurons and metaphase kinetochores in dividing human cells. The software is available at http://hmm-bayes.org/.</p>
},
	issn = {1548-7105},
	doi = {10.1038/nmeth.3483},
	author = {Monnier, Nilah and Barry, Zachary and Park, Hye Yoon and Su, Kuan-Chung and Katz, Zachary and English, Brian P and Dey, Arkajit and Pan, Keyao and Cheeseman, Iain M and Singer, Robert H and Bathe, Mark}
}
