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Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2011
Korotkov KV, Gonen T, Hol WGJ.
2011. Secretins: dynamic channels for protein transport across membranes.. Trends in Biochemical Sciences. 36(8):433-43.
Budzinski KL, Sgro AE, Fujimoto BS, Gadd JC, Shuart NG, Gonen T, Bajjaleih SM, Chiu DT.
2011. Synaptosomes as a platform for loading nanoparticles into synaptic vesicles.. ACS Chemical Neuroscience. 2(5):236-241.
2012
Gold MG, Reichow SL, O’Neill SE, Weisbrod CR, Langeberg LK, Bruce JE, Gonen T, Scott JD.
2012. AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency.. EMBO Molecular Medicine. 4(1):15-26.
King NP, Sheffler W, Sawaya MR, Vollmar BS, Sumida JP, André I, Gonen T, Yeates TO, Baker D.
2012. Computational design of self-assembling protein nanomaterials with atomic level accuracy.. Science. 336(6085):1171-4.
Jiang Q-X, Gonen T.
2012. The influence of lipids on voltage-gated ion channels.. Current Opinion in Structural Biology. 22(4):529-36.
Lo S-Y, Brett CL, Plemel RL, Vignali M, Fields S, Gonen T, Merz AJ.
2012. Intrinsic tethering activity of endosomal Rab proteins.. Nature Structural & Molecular Biology. 19(1):40-7.
Umbreit NT, Gestaut DR, Tien JF, Vollmar BS, Gonen T, Asbury CL, Davis TN.
2012. The Ndc80 kinetochore complex directly modulates microtubule dynamics.. Proceedings of the National Academy of Sciences of the United States of America. 109(40):16113-8.
Gonen S, Akiyoshi B, Iadanza MG, Shi D, Duggan N, Biggins S, Gonen T.
2012. The structure of purified kinetochores reveals multiple microtubule-attachment sites.. Nature Structural & Molecular Biology. 19(9):925-9.
2013
Reichow SL, Clemens DM, J Freites A, Németh-Cahalan KL, Heyden M, Tobias DJ, Hall JE, Gonen T.
2013. Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.. Nature Structural & Molecular Biology. 20(9):1085-92.
Zheng H, Wisedchaisri G, Gonen T.
2013. Crystal structure of a nitrate/nitrite exchanger.. Nature. 497(7451):647-51.
Silverman JM, Agnello DM, Zheng H, Andrews BT, Li M, Catalano CE, Gonen T, Mougous JD.
2013. Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates.. Molecular Cell. 51(5):584-93.
Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS.
2013. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.. Nature Structural & Molecular Biology. 20(2):150-8.
F Smith D, Reichow SL, Esseltine JL, Shi D, Langeberg LK, Scott JD, Gonen T.
2013. Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.. eLife. 2:e01319.
Gold MG, Gonen T, Scott JD.
2013. Local cAMP signaling in disease at a glance.. Journal of Cell Science. 126(Pt 20):4537-43.
Nannenga BL, Iadanza MG, Vollmar BS, Gonen T.
2013. Overview of electron crystallography of membrane proteins: crystallization and screening strategies using negative stain electron microscopy.. Current Protocols in Protein Science . Chapter 17:Unit17.15.
Shi D, Nannenga BL, Iadanza MG, Gonen T.
2013. Three-dimensional electron crystallography of protein microcrystals.. eLife. 2:01345.
2014
King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D.
2014. Accurate design of co-assembling multi-component protein nanomaterials.. Nature. 510(7503):103-8.
Anderson TM, Clay MC, Cioffi AG, Diaz KA, Hisao GS, Tuttle MD, Nieuwkoop AJ, Comellas G, Maryum N, Wang S et al..
2014. Amphotericin forms an extramembranous and fungicidal sterol sponge.. Nature Chemical Biology. 10(5):400-6.
Gonen T, Waksman G.
2014. Editorial overview: Membranes: recent methods in the study of membrane protein structure.. Current Opinion in Structural Biology. 27:iv-v.
Huang P-S, Oberdorfer G, Xu C, Pei XY, Nannenga BL, Rogers JM, DiMaio F, Gonen T, Luisi B, Baker D.
2014. High thermodynamic stability of parametrically designed helical bundles.. Science. 346(6208):481-5.
Nannenga BL, Shi D, Leslie AGW, Gonen T.
2014. High-resolution structure determination by continuous-rotation data collection in MicroED.. Nature Methods. 11(9):927-30.
Nannenga BL, Gonen T.
2014. Protein structure determination by MicroED.. Current Opinion in Structural Biology. 27C:24-31.
Wisedchaisri G, Park M-S, Iadanza MG, Zheng H, Gonen T.
2014. Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.. Nature Communication. 5:4521.
Nannenga BL, Shi D, Hattne J, Reyes FE, Gonen T.
2014. Structure of catalase determined by MicroED.. eLife. 3:e03600.