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Fly-eFISH

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Fly-eFISH is a Small Team Project that is describing aspects of Drosophila melanogaster neural communication beyond what can be currently learned from connectomes derived from electron microscopic images. The project’s initial goals are to describe neuropeptide (NP) signaling in the fly central nervous system (CNS) and digestive system.

Our first project will use the EASI-FISH technique (see Prior Work and Approach) to map NP expression both across the CNS and in specific cell types targeted by genetic driver lines.