Cortical rewiring and information storage.

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Nature. 2004 Oct 14;431(7010):782-8

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Cortical rewiring and information storage. Svoboda Lab

Chklovskii DB, Mel B, Svoboda K

Note: Research in this publication was not performed at Janelia.

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Abstract

Current thinking about long-term memory in the cortex is focused on changes in the strengths of connections between neurons. But ongoing structural plasticity in the adult brain, including synapse formation/elimination and remodelling of axons and dendrites, suggests that memory could also depend on learning-induced changes in the cortical 'wiring diagram'. Given that the cortex is sparsely connected, wiring plasticity could provide a substantial boost in storage capacity, although at a cost of more elaborate biological machinery and slower learning.

PMID: 15483599 [PubMed - indexed for MEDLINE]

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Cortical rewiring and information storage.

Note: Research in this publication was not performed at Janelia.

Abstract

PMID: 15483599 [PubMed - indexed for MEDLINE]