Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila.

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Current Biology. 2000 Feb 24;10(4):187-94

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Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Heberlein Lab

Bainton RJ, Tsai LT, Singh CM, Moore MS, Neckameyer WS, Heberlein U

Note: Research in this publication was not performed at Janelia.

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Abstract

Drugs of abuse have a common property in mammals, which is their ability to facilitate the release of the neurotransmitter and neuromodulator dopamine in specific brain regions involved in reward and motivation. This increase in synaptic dopamine levels is believed to act as a positive reinforcer and to mediate some of the acute responses to drugs. The mechanisms by which dopamine regulates acute drug responses and addiction remain unknown.

PMID: 10704411 [PubMed - indexed for MEDLINE]

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Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila.

Note: Research in this publication was not performed at Janelia.

Abstract

PMID: 10704411 [PubMed - indexed for MEDLINE]

Janelia Authors