Frealign: an exploratory tool for single-particle cryo-EM.

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Methods in Enzymology. 2016 Jun 07;. doi: 10.1016/bs.mie.2016.04.013

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Frealign: an exploratory tool for single-particle cryo-EM. Grigorieff Lab

Grigorieff N

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Abstract

Frealign is a software tool designed to process electron microscope images of single molecules and complexes to obtain reconstructions at the highest possible resolution. It provides a number of refinement parameters and options that allow users to tune their refinement to achieve specific goals, such as masking to classify selected regions within a particle, control over the refinement of specific alignment parameters to accommodate various data collection schemes, refinement of pseudosymmetric particles, and generation of initial maps. This chapter provides a general overview of Frealign functions and a more detailed guide to using Frealign in typical scenarios.

PMID: 27572728 [PubMed - indexed for MEDLINE]

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Frealign: an exploratory tool for single-particle cryo-EM.

Abstract

PMID: 27572728 [PubMed - indexed for MEDLINE]

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