Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy.

Our Research / Publications

janelia7_blocks-janelia7_biblio_header | block

Current Opinion in Structural Biology. 2011 Apr;21(2):265-73. doi: 10.1016/j.sbi.2011.01.008

View Article on

Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Grigorieff Lab

Grigorieff N, Harrison SC

Note: Research in this publication was not performed at Janelia.

janelia7_blocks-janelia7_biblio_abstract | block

Abstract

Nine different near-atomic resolution structures of icosahedral viruses, determined by electron cryo-microscopy and published between early 2008 and late 2010, fulfil predictions made 15 years ago that single-particle cryo-EM techniques could visualize molecular detail at 3-4A resolution. This review summarizes technical developments, both in instrumentation and in computation, that have led to the new structures, which advance our understanding of virus assembly and cell entry.

PMID: 21333526 [PubMed - indexed for MEDLINE]

node:body | entity_field

Main Menu (Mobile)- Block

Main Menu - Block

Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy.

Note: Research in this publication was not performed at Janelia.

Abstract

PMID: 21333526 [PubMed - indexed for MEDLINE]

Janelia Authors