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janelia7_blocks-janelia7_biblio_header | block
Nature Reviews. Molecular Cell Biology. 2004 May;5(5):403-10. doi: 10.1073/pnas.1100640108
Regulatory diversity among metazoan co-activator complexes. Tjian Lab

Taatjes DJ, Marr MT, Tjian R
Note: Research in this publication was not performed at Janelia.
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Abstract
Transcription is a stepwise process that involves many specialized proteins and protein complexes, all of which must work together to express a given gene in a spatially and temporally regulated manner. An integral step in this regulatory process is carried out by large, multisubunit co-activator complexes, which have diverse roles in transcriptional control. Their diversity and large size allows for many potential regulatory inputs, but how is the versatility and specificity of these co-activator complexes determined?
PMID: 15122353 [PubMed - indexed for MEDLINE]
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Janelia Authors
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