Main Menu (Mobile)- Block
MENU
- Overview
-
Support Teams
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
- Open Science
- You + Janelia
- About Us
Labs:
Project Teams:
Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
janelia7_blocks-janelia7_biblio_header | block
Organic Letters. 2006 Nov 23;8(24):5637-40. doi: 10.1021/ol062390l
Stereochemically general approach to adjacent bis(tetrahydrofuran) cores of annonaceous acetogenins.
Wysocki LM, Dodge MW, Voight EA, Burke SD
Note: Research in this publication was not performed at Janelia.
janelia7_blocks-janelia7_biblio_abstract | block
Abstract
A series of six 2,5-disubstituted adjacent bis(tetrahydrofuran) stereoisomers with trans/erythro/cis, trans/threo/trans, or cis/threo/cis relative stereochemistry have been synthesized from known dihydroxycyclooctenes via ring opening/cross metathesis and Pd(0)-mediated asymmetric double cycloetherification. The stereochemistry of four of these isomers has been found in the biologically active annonaceous acetogenin natural products. [reaction: see text].
PMID: 17107091 [PubMed - indexed for MEDLINE]
node:body | entity_field
janelia7_blocks-janelia7_biblio_authors | block
Janelia Authors
janelia7_blocks-janelia7_biblio_tools | block