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Molecular Cell. 2018 Apr 19;70(2):195-196. doi: 10.1016/j.molcel.2018.04.004
Transvection Goes Live-Visualizing Enhancer-Promoter Communication between Chromosomes.
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Abstract
Lim et al. (2018) use live imaging in Drosophila embryos to show that enhancers can drive transcription from promoters on another chromosome when they are in close proximity. In addition, they show that multiple promoters can access the same enhancer without competition, potentially sharing a pool of factors in a transcriptional "hub."
PMID: 29677489 [PubMed - indexed for MEDLINE]
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Janelia Authors
Robert Singer
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