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Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2008
Shao L, Isaac B, Uzawa S, Agard DA, Sedat JW, Gustafsson MGL.
2008. I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions.. Biophysical Journal. 94(12):4971-83.
Schermelleh L, Carlton PM, Haase S, Shao L, Winoto L, Kner P, Burke B, M Cardoso C, Agard DA, Gustafsson MGL et al..
2008. Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy.. Science. 320(5881):1332-6.
Gustafsson MGL, Shao L, Carlton PM, Wang CJRachel, Golubovskaya IN, W Cande Z, Agard DA, Sedat JW.
2008. Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination.. Biophysical Journal. 94(12):4957-70.
2010
Carlton PM, Boulanger J, Kervrann C, Sibarita J-B, Salamero J, Gordon-Messer S, Bressan D, Haber JE, Haase S, Shao L et al..
2010. Fast live simultaneous multiwavelength four-dimensional optical microscopy.. Proceedings of the National Academy of Sciences of the United States of America. 107(37):16016-22.
2011
Shao L, Kner P, E Rego H, Gustafsson MGL.
2011. Super-resolution 3D microscopy of live whole cells using structured illumination.. Nature Methods. 8:1044-6.
2012
Gao L, Shao L, Higgins CD, Poulton JS, Peifer M, Davidson MW, Wu X, Goldstein B, Betzig E.
2012. Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens.. Cell. 151(6):1370-85.
E Rego H, Shao L, Macklin JJ, Winoto L, Johansson GA, Kamps-Hughes N, Davidson MW, Gustafsson MGL.
2012. Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution.. Proceedings of the National Academy of Sciences of the United States of America. 109:E135-43.
Fiolka R, Shao L, E Rego H, Davidson MW, Gustafsson MGL.
2012. Time-lapse two-color 3D imaging of live cells with doubled resolution using structured illumination.. Proceedings of the National Academy of Sciences of the United States of America. 109(14):5311-5.
2013
2014
Gao L, Shao L, Chen B-C, Betzig E.
2014. 3D live fluorescence imaging of cellular dynamics using Bessel beam plane illumination microscopy.. Nature Protocols. 9:1083-101.
Burnette DT, Shao L, Ott C, Pasapera AM, Fischer RS, Baird MA, Der Loughian C, Delanoe-Ayari H, Paszek MJ, Davidson MW et al..
2014. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells.. Journal of Cell Biology. 205(1):83-96.
Burnette DT, Shao L, Ott C, Pasapera AM, Fischer RS, Baird MA, Der Loughian C, Delanoe-Ayari H, Paszek MJ, Davidson MW et al..
2014. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells.. The Journal of cell biology. 205(1):83-96.
Chen B-C, Legant WR, Wang K, Shao L, Milkie DE, Davidson MW, Janetopoulos C, Wu XS, Hammer JA, Liu Z et al..
2014. Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution.. Science. 346(6208):1257998.
Beach JR, Shao L, Remmert K, Li D, Betzig E, Hammer JA.
2014. Nonmuscle myosin II isoforms coassemble in living cells.. Current Biology. 24(10):1160-6.
Shao L, E Rego H.
2014. Structured illumination microscopy (Chapter 15.). Fluorescence Microscopy: Super-resolution and other novel techniques. :213–225.
2015
Li D, Shao L, Chen B-C, Zhang X, Zhang M, Moses B, Milkie DE, Beach JR, Hammer JA, Pasham M et al..
2015. Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics.. Science (New York, N.Y.). 349(6251)
Billington N, Beach JR, Heissler SM, Remmert K, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D, Yang Y et al..
2015. Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filaments.. Current Biology. 25(7):942-8.
2016
Hayer A, Shao L, Chung M, Joubert L-M, Yang HWon, Tsai F-C, Bisaria A, Betzig E, Meyer T.
2016. Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells.. Nature Cell Biology. 18(12):1311-23.
Murugesan S, Hong J, Yi J, Li D, Beach JR, Shao L, Meinhardt J, Madison G, Wu X, Betzig E et al..
2016. Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse.. The Journal of Cell Biology. 215(3):383-99.
2017
Beach JR, Bruun KS, Shao L, Li D, Swider Z, Remmert K, Zhang Y, Conti MA, Adelstein RS, Rusan NM et al..
2017. Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments.. Nature Cell Biology. 19(2):85-93.
Ashdown GW, Burn GL, Williamson DJ, Pandzic E, Peters R, Holden M, Ewers H, Shao L, Wiseman PW, Owen DM.
2017. Live-cell super-resolution reveals F-Actin and plasma membrane dynamics at the T Cell synapse.. Biophysical Journal. 112(8):1703-13.