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Labs:
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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2006
Lavis LD, Chao T-Y, Raines RT.
2006. Fluorogenic label for biomolecular imaging.. ACS Chemical Biology. 1(4):252-60.
2007
R Johnson J, Chao T-Y, Lavis LD, Raines RT.
2007. Cytotoxic ribonucleases: the dichotomy of Coulombic forces.. Biochemistry. 46(36):10308-16.
R Johnson J, Lavis LD, Raines RT.
2007. Intraspecies regulation of ribonucleolytic activity.. Biochemistry. 46:13131-40.
Lavis LD, Rutkoski TJ, Raines RT.
2007. Tuning the pK(a) of fluorescein to optimize binding assays.. Analytical Chemistry. 79(17):6775-82.
2008
Lavis LD, Raines RT.
2008. Bright ideas for chemical biology.. ACS Chemical Biology. 3:142-55.
Yatzeck MM, Lavis LD, Chao T-Y, Chandran SS, Raines RT.
2008. A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells.. Bioorganic & Medicinal Chemistry Letters. 18(22):5864-6.
2009
Watkins RW, Lavis LD, Kung VM, Los GV, Raines RT.
2009. Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells.. Organic & Biomolecular Chemistry. 7(19):3969-75.
Turcotte RF, Lavis LD, Raines RT.
2009. Onconase cytotoxicity relies on the distribution of its positive charge.. The FEBS Journal. 276(14):3846-57.
2010
2011
Wysocki LM, Lavis LD.
2011. Advances in the chemistry of small molecule fluorescent probes.. Current Opinion in Chemical Biology. 15(6):752-9.
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.
2011. Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
Lavis LD.
2011. Histochemistry: live and in color.. The Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society. 59:139-45.
Lavis LD, Chao T-Y, Raines RT.
2011. Synthesis and utility of fluorogenic acetoxymethyl ethers.. Chemical Science. 2(3):521-30.
2012
Mütze J, Iyer V, Macklin JJ, Colonell J, Karsh B, sek Z\vek Petrá\, Schwille P, Looger LL, Lavis LD, Harris TD.
2012. Excitation spectra and brightness optimization of two-photon excited probes.. Biophysical Journal. 102(4):934-44.
Tian L, Yang Y, Wysocki LM, Arnold AC, Hu A, Ravichandran B, Sternson SM, Looger LL, Lavis LD.
2012. Selective esterase-ester pair for targeting small molecules with cellular specificity.. Proceedings of the National Academy of Sciences of the United States of America. 109:4756-61.
Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, R Johnson J.
2012. The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima.. Biochimica et Biophysica Acta. 1824(9):1024-30.
2013
Banghart MR, Williams JT, Shah RC, Lavis LD, Sabatini BL.
2013. Caged naloxone reveals opioid signaling deactivation kinetics.. Molecular Pharmacology. 84(5):687-95.
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.
2013. Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.
2013. The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Ellis EE, Adkins CT, Galovska NM, Lavis LD, R Johnson J.
2013. Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase.. Chembiochem : A European Journal of Chemical Biology. 14(9):1134-44.
Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L et al..
2013. Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.. J Biol Chem. 288(15):10522-35.