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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2015
Knight SC, Xie L, Deng W, Guglielmi B, Witkowsky LB, Bosanac L, Zhang ET, Beheiry MEl, Masson J-B, Dahan M et al..
2015. Dynamics of CRISPR-Cas9 genome interrogation in living cells.. Science (New York, N.Y.). 350(6262):823-6.
2017
Xie L, Torigoe SE, Xiao J, Mai DH, Li L, Davis FP, Dong P, Marie-Nelly H, Grimm J, Lavis L et al..
2017. A dynamic interplay of enhancer elements regulates Klf4 expression in naïve pluripotency.. Genes & Development. 31(17):1795-1808.
2020
Xie L, Dong P, Chen X, Hsieh T-HS, Banala S, De Marzio M, English BP, Qi Y, Jung SKyoung, Kieffer-Kwon K-R et al..
2020. 3D ATAC-PALM: super-resolution imaging of the accessible genome.. Nature Methods. 17(4):430-6.
Grimm JB, Tkachuk AN, Xie L, Choi H, Mohar B, Falco N, Schaefer K, Patel R, Zheng Q, Liu Z et al..
2020. A general method to optimize and functionalize red-shifted rhodamine dyes.. Nature Methods.
2021
Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, González RChamorro, Weiser NE et al..
2021. ecDNA hubs drive cooperative intermolecular oncogene expression.. Nature. 600(7890):731-6.
Grimm JB, Xie L, Casler JC, Patel R, Tkachuk AN, Falco N, Choi H, Lippincott-Schwartz J, Brown TA, Glick BS et al..
2021. A general method to improve fluorophores using deuterated auxochromes.. JACS Au. 1(5):690-6.
Xie L, Liu Z.
2021. Single-cell imaging of genome organization and dynamics.. Molecular Systems Biology. 17(7):e9653.
2022
Xie L, Dong P, Qi Y, Hsieh T-HS, English BP, Jung S, Chen X, De Marzio M, Casellas R, Chang HY et al..
2022. BRD2 compartmentalizes the accessible genome.. Nature Genetics. 54(4):481-491.