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Neuroendocrinology. 2014 Nov 6;507(7491):238-42. doi: 10.1159/000369072
Agouti-related protein neuron circuits that regulate appetite.
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Abstract
New tools for mapping and manipulating molecularly defined neural circuits have improved understanding of how the central nervous system regulates appetite. Studies focused on AGRP neurons, a starvation-sensitive hypothalamic population, have identified multiple circuit elements that can elicit or suppress feeding behavior. Distinct axon projections of this neuron population point to different circuits that regulate long-term appetite, short-term feeding, or visceral malaise-mediated anorexia. Here, we review recent studies examining these neural circuits that control food intake. © 2014 S. Karger AG, Basel.
PMID: 25402352 [PubMed - indexed for MEDLINE]
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Janelia Authors
Scott Sternson
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