HortaCloud: An Open and Collaborative Platform for Whole Brain Neuronal Reconstructions

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bioRxiv. 2025 Mar 13;. doi: 10.1101/2025.03.13.642887

HortaCloud: An Open and Collaborative Platform for Whole Brain Neuronal Reconstructions MouseLightScientific Computing Software

Rokicki K, Schauder D, Olbris DJ, Goina C, Clements J, Edson P, Kawase T, Svirskas R, Arshadi C, Feng D, Chandrashekar J, Ferreira TA, Team MouseLight

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Abstract

HortaCloud is a cloud-based, open-source platform designed to facilitate the collaborative reconstruction of long-range projection neurons from whole-brain light microscopy data. By providing virtual environments directly within the cloud, it eliminates the need for costly and time-consuming data downloads, allowing researchers to work efficiently with terabyte- scale volumetric datasets. Standardization of computational resources in the cloud make deployment easier and more predictable. The pay-as-you-go cloud model reduces adoption barriers by eliminating upfront investments in expensive hardware. Finally, HortaCloud’s decentralized architecture enables global collaboration between researchers and between institutions.

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HortaCloud: An Open and Collaborative Platform for Whole Brain Neuronal Reconstructions

Abstract

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