Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms

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Current Opinion in Neurobiology. 2015 Apr 1;31:156-163. doi: https://doi.org/10.1016/j.conb.2014.10.012

Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms Otopalik Lab

Marder Eve, Goeritz Marie, Otopalik Adriane

Note: Research in this publication was not performed at Janelia.

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Abstract

Small central pattern generating circuits found in invertebrates have significant advantages for the study of the circuit mechanisms that generate brain rhythms. Experimental and computational studies of small oscillatory circuits reveal that similar rhythms can arise from disparate mechanisms. Animal-to-animal variation in the properties of single neurons and synapses may underly robust circuit performance, and can be revealed by perturbations. Neuromodulation can produce altered circuit performance but also ensure reliable circuit function.

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Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms

Note: Research in this publication was not performed at Janelia.

Abstract

Janelia Authors