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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2018
Hattne J, Shi D, Glynn C, Zee C-T, Gallagher-Jones M, Martynowycz MW, Rodriguez JA, Gonen T.
2018. Analysis of global and site-specific radiation damage in cryo-EM.. Structure (London, England : 1993). 26(5):759-66.
Purdy MD, Shi D, Chrustowicz J, Hattne J, Gonen T, Yeager M.
2018. MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat.. Proceedings of the National Academy of Sciences of the United States of America. 115(52):13258-63.
2017
Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S et al..
2017. Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.. eLife. 6
M de la Cruz J, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SKyung et al..
2017. Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.. Nature Methods. 14(4):399-402.
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J et al..
2017. Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design.. The Journal of Biological Chemistry. 293(8):2888-902.
2016
Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS.
2016. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.. Proceedings of the National Academy of Sciences of the United States of America. 113(40):11232-6.
Shi D, Nannenga BL, M de la Cruz J, Liu J, Sawtelle S, Calero G, Reyes FE, Hattne J, Gonen T.
2016. The collection of MicroED data for macromolecular crystallography.. Nature Protocols. 11(5):895-904.
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang P-S, Ravichandran R et al..
2016. Design of a hyperstable 60-subunit protein icosahedron.. Nature.
Hattne J, Shi D, M de la Cruz J, Reyes FE, Gonen T.
2016. Modeling truncated pixel values of faint reflections in MicroED images.. Journal of Applied Crystallography. 49(3)
2015
Hattne J, Reyes FE, Nannenga BL, Shi D, M de la Cruz J, Leslie AGW, Gonen T.
2015. MicroED data collection and processing.. Acta Crystallographica Section A: Foundations & Advances. 71(Pt 4):353-60.
Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M et al..
2015. Structure of the toxic core of α-synuclein from invisible crystals.. Nature. 525(7570):486-90.
2014
Nannenga BL, Shi D, Leslie AGW, Gonen T.
2014. High-resolution structure determination by continuous-rotation data collection in MicroED.. Nature Methods. 11(9):927-30.
Nannenga BL, Shi D, Hattne J, Reyes FE, Gonen T.
2014. Structure of catalase determined by MicroED.. eLife. 3:e03600.
2013
Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS.
2013. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.. Nature Structural & Molecular Biology. 20(2):150-8.
F Smith D, Reichow SL, Esseltine JL, Shi D, Langeberg LK, Scott JD, Gonen T.
2013. Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.. eLife. 2:e01319.
Shi D, Nannenga BL, Iadanza MG, Gonen T.
2013. Three-dimensional electron crystallography of protein microcrystals.. eLife. 2:01345.
2012
Gonen S, Akiyoshi B, Iadanza MG, Shi D, Duggan N, Biggins S, Gonen T.
2012. The structure of purified kinetochores reveals multiple microtubule-attachment sites.. Nature Structural & Molecular Biology. 19(9):925-9.