Biblio

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Author Title Type [ Year(Asc)]
Filters: Author is Brown, Timothy A  [Clear All Filters]
2025
Mohar B, Michel G, Wang Y-Z, Hernandez V, Grimm JB, Park J-Y, Patel R, Clarke M, Brown TA, Bergmann C et al..  2025.  DELTA: A method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning.. Nat Neurosci.
Marvin JS, Mächler P, Meng C, Ates T, Patel RH, Adhikari R, Makurath MA, Ku Z, Feliciano D, Atasoy D et al..  2025.  iGlucoSnFR2: A genetically encoded fluorescent sensor for measuring intracellular or extracellular glucose in vivo in mouse brain.. Sci Adv. 11(46):eadz3889.
2024
Davidsen K, Marvin JS, Aggarwal A, Brown TA, Sullivan LB.  2024.  An engineered biosensor enables dynamic aspartate measurements in living cells.. Elife. 12
2020
Grimm JB, Tkachuk AN, Xie L, Choi H, Mohar B, Falco N, Schaefer K, Patel R, Zheng Q, Liu Z et al..  2020.  A general method to optimize and functionalize red-shifted rhodamine dyes.. Nature Methods.
Binns TC, Ayala AX, Grimm JB, Tkachuk AN, Castillon GA, Phan S, Zhang L, Brown TA, Liu Z, Adams SR et al..  2020.  Rational design of bioavailable photosensitizers for manipulation and imaging of biological systems.. Cell Chemical Biology. 27(8):1063-72.
2018
Moeyaert B, Holt G, Madangopal R, Perez-Alvarez A, Fearey BC, Trojanowski NF, Ledderose J, Zolnik TA, Das A, Patel D et al..  2018.  Improved methods for marking active neuron populations.. Nature Communications. 9(1):4440.
2017
Grimm JB, Muthusamy AK, Liang Y, Brown TA, Lemon WC, Patel R, Lu R, Macklin JJ, Keller PJ, Ji N et al..  2017.  A general method to fine-tune fluorophores for live-cell and in vivo imaging.. Nature Methods. 14(10):987-994.
Grimm JB, Brown TA, Tkachuk AN, Lavis LD.  2017.  General synthetic method for Si-Fluoresceins and Si-Rhodamines.. ACS Central Science. 3(9):975-85.
Grimm JB, Brown TA, English BP, Lionnet T, Lavis LD.  2017.  Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments.. Methods in Molecular Biology (Clifton, N.J.). 1663:179-188.
2016
Lavis LD, Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z et al..  2016.  Bright photoactivatable fluorophores for single-molecule imaging.. Nature Methods. 13(12):985-8.
Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.  2016.  High-density three-dimensional localization microscopy across large volumes.. Nature Methods.
Rinholm JE, Vervaeke K, Tadross MR, Tkachuk AN, Kopek BG, Brown TA, Bergersen LH, Clayton DA.  2016.  Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths.. Glia. 64(5):810-25.
Grimm JB, Gruber TD, Ortiz G, Brown TA, Lavis LD.  2016.  Virginia Orange: A versatile, red-shifted fluorescein scaffold for single- and dual-input fluorogenic probes.. Bioconjugate Chemistry. 27(2):474-80.
2015
Brown TA, Tkachuk AN, Clayton DA.  2015.  Mitochondrial transcription factor A (TFAM) binds to RNA containing 4-way junctions and mitochondrial tRNA.. PloS one. 10(11):e0142436.
2011
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.  2011.  Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
Brown TA, Tkachuk AN, Shtengel G, Kopek BG, Bogenhagen DF, Hess HF, Clayton DA.  2011.  Superresolution fluorescence imaging of mitochondrial nucleoids reveals their spatial range, limits, and membrane interaction.. Molecular and Cellular Biology. 31:4994-5010.
2010
Brown TA, Fetter RD, Tkachuk AN, Clayton DA.  2010.  Approaches toward super-resolution fluorescence imaging of mitochondrial proteins using PALM.. Methods. 51(4):458-63.
2008
Brown TA, Tkachuk AN, Clayton DA.  2008.  Native R-loops persist throughout the mouse mitochondrial DNA genome.. The Journal of Biological Chemistry. 283(52):36743-51.
2006
Brown TA, Clayton DA.  2006.  Genesis and wanderings: origins and migrations in asymmetrically replicating mitochondrial DNA.. Cell Cycle. 5(9):917-21.
2005
Brown TA, Cecconi C, Tkachuk AN, Bustamante C, Clayton DA.  2005.  Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism.. Genes & Development. 19(20):2466-76.
2004
Kraytsberg Y, Schwartz M, Brown TA, Ebralidse K, Kunz WS, Clayton DA, Vissing J, Khrapko K.  2004.  Recombination of human mitochondrial DNA.. Science. 304(5673):981.
2002
Clark KM, Brown TA, Davidson MM, Papadopoulou LC, Clayton DA.  2002.  Differences in nuclear gene expression between cells containing monomer and dimer mitochondrial genomes.. Gene. 286(1):91-104.
Brown TA, Clayton DA.  2002.  Release of replication termination controls mitochondrial DNA copy number after depletion with 2’,3’-dideoxycytidine.. Nucleic Acids Research. 30(9):2004-10.