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- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
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- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
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- Vivarium
Export 54 results:
Author Title Type [ Year
Filters: Author is Grimm, Jonathan B [Clear All Filters]
2017
Grimm JB, Brown TA, English BP, Lionnet T, Lavis LD.
2017. Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments.. Methods in Molecular Biology (Clifton, N.J.). 1663:179-188.
Liu H, Dong P, Ioannou MS, Li L, Shea J, H Pasolli A, Grimm JB, Rivlin PK, Lavis LD, Koyama M et al..
2017. Visualizing long-term single-molecule dynamics in vivo by stochastic protein labeling.. Proceedings of the National Academy of Sciences of the United States of America. 115(2):343-8.
2016
Lavis LD, Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z et al..
2016. Bright photoactivatable fluorophores for single-molecule imaging.. Nature Methods. 13(12):985-8.
Heckman LM, Grimm JB, Schreiter ER, Kim C, Verdecia MA, Shields BC, Lavis LD.
2016. Design and synthesis of a calcium-sensitive photocage.. Angewandte Chemie (International ed. in English).
Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.
2016. Glutamate-induced RNA localization and translation in neurons.. Proceedings of the National Academy of Sciences of the United States of America.
Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.
2016. High-density three-dimensional localization microscopy across large volumes.. Nature Methods.
Zhen CYu, Tatavosian R, Huynh TNgoc, Duc HNguyen, Das R, Kokotovic M, Grimm JB, Lavis LD, Lee J, Mejia FJ et al..
2016. Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.. eLife. 5
Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG et al..
2016. Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.. Genes and Development. 30:2106-18.
Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.
2016. Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.. eLife. 5
Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL.
2016. Real-time quantification of single RNA translation dynamics in living cells.. Science. 352(6292):1425-9.
Cho W-K, Jayanth N, English BP, Inoue T, J Andrews O, Conway W, Grimm JB, Spille J-H, Lavis LD, Lionnet T et al..
2016. RNA Polymerase II cluster dynamics predict mRNA output in living cells.. eLife. 5
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..
2015. A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.
2015. Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.
2014. 3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.
2014. Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2013
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.
2013. Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.
2013. The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Kopek BG, Shtengel G, Grimm JB, Clayton DA, Hess HF.
2013. Correlative photoactivated localization and scanning electron microscopy.. PLoS One. 8(10):e77209.
2011
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.
2011. Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
2009
Grimm JB, Wilson KJ, Witter DJ.
2009. A divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.. The Journal of Organic Chemistry. 74(16):6390-3.
Heidebrecht RW, Chenard M, Close J, Dahlberg WK, Fleming J, Grimm JB, Hamill JE, Harsch A, Haines BB, Hughes B et al..
2009. Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).. Bioorganic & Medicinal Chemistry Letters. 19(7):2053-8.
2008
Wilson KJ, Witter DJ, Grimm JB, Siliphaivanh P, Otte KM, Kral AM, Fleming JC, Harsch A, Hamill JE, Cruz JC et al..
2008. Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).. Bioorganic & Medicinal Chemistry Letters. 18(6):1859-63.