Biblio

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2017
Martineau M, Somasundaram A, Grimm JB, Gruber TD, Choquet D, Taraska JW, Lavis LD, Perrais D.  2017.  Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis.. Nature Communications. 8(1):1412.
Liu H, Dong P, Ioannou MS, Li L, Shea J, H Pasolli A, Grimm JB, Rivlin PK, Lavis LD, Koyama M et al..  2017.  Stochastic protein labeling enables long-term single molecule observation in vivo.. bioRxiv.
Grimm JB, Brown TA, English BP, Lionnet T, Lavis LD.  2017.  Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments.. Methods in Molecular Biology (Clifton, N.J.). 1663:179-188.
Liu H, Dong P, Ioannou MS, Li L, Shea J, H Pasolli A, Grimm JB, Rivlin PK, Lavis LD, Koyama M et al..  2017.  Visualizing long-term single-molecule dynamics in vivo by stochastic protein labeling.. Proceedings of the National Academy of Sciences of the United States of America. 115(2):343-8.
2016
Lavis LD, Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z et al..  2016.  Bright photoactivatable fluorophores for single-molecule imaging.. Nature Methods. 13(12):985-8.
Heckman LM, Grimm JB, Schreiter ER, Kim C, Verdecia MA, Shields BC, Lavis LD.  2016.  Design and synthesis of a calcium-sensitive photocage.. Angewandte Chemie (International ed. in English).
Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.  2016.  Glutamate-induced RNA localization and translation in neurons.. Proceedings of the National Academy of Sciences of the United States of America.
Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.  2016.  High-density three-dimensional localization microscopy across large volumes.. Nature Methods.
Zhen CYu, Tatavosian R, Huynh TNgoc, Duc HNguyen, Das R, Kokotovic M, Grimm JB, Lavis LD, Lee J, Mejia FJ et al..  2016.  Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.. eLife. 5
Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG et al..  2016.  Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.. Genes and Development. 30:2106-18.
Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.  2016.  Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.. eLife. 5
Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL.  2016.  Real-time quantification of single RNA translation dynamics in living cells.. Science. 352(6292):1425-9.
Cho W-K, Jayanth N, English BP, Inoue T, J Andrews O, Conway W, Grimm JB, Spille J-H, Lavis LD, Lionnet T et al..  2016.  RNA Polymerase II cluster dynamics predict mRNA output in living cells.. eLife. 5
Swinstead EE, Miranda TB, Paakinaho V, Baek S, Goldstein I, Hawkins M, Karpova TS, Ball D, Mazza D, Lavis LD et al..  2016.  Steroid receptors reprogram FoxA1 occupancy through dynamic chromatin transitions.. Cell.
Grimm JB, Gruber TD, Ortiz G, Brown TA, Lavis LD.  2016.  Virginia Orange: A versatile, red-shifted fluorescein scaffold for single- and dual-input fluorogenic probes.. Bioconjugate Chemistry. 27(2):474-80.
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..  2015.  A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.  2015.  Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.  2014.  3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.  2014.  Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2013
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.  2013.  Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.  2013.  The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Kopek BG, Shtengel G, Grimm JB, Clayton DA, Hess HF.  2013.  Correlative photoactivated localization and scanning electron microscopy.. PLoS One. 8(10):e77209.
2011
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.  2011.  Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
Grimm JB, Lavis LD.  2011.  Synthesis of rhodamines from fluoresceins using Pd-catalyzed C-N cross-coupling.. Organic Letters. 13(24):6354-7.
2009
Grimm JB, Wilson KJ, Witter DJ.  2009.  A divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.. The Journal of Organic Chemistry. 74(16):6390-3.