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janelia7_blocks-janelia7_biblio_header | block
Current Opinion in Neurobiology. 2013 Feb;23(1):119-26. doi: 10.1016/j.conb.2012.11.001
Optogenetics in a transparent animal: circuit function in the larval zebrafish. Ahrens Lab
Portugues R, Severi KE, Wyart C, Ahrens MB
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Abstract
Optogenetic tools can be used to manipulate neuronal activity in a reversible and specific manner. In recent years, such methods have been applied to uncover causal relationships between activity in specified neuronal circuits and behavior in the larval zebrafish. In this small, transparent, genetic model organism, noninvasive manipulation and monitoring of neuronal activity with light is possible throughout the nervous system. Here we review recent work in which these new tools have been applied to zebrafish, and discuss some of the existing challenges of these approaches.
PMID: 23246238 [PubMed - indexed for MEDLINE]
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janelia7_blocks-janelia7_biblio_authors | block
Janelia Authors
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