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Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
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More in this Support Team
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Support Teams / Mass Spectrometry
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What We Do
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The mass spectrometry department at Janelia provides on campus laboratories with a wide range of analytical capabilities to support their research programs. We are equipped with state-of-the-art LC-MS/MS systems which enables the development and the applications of highly sensitive and advanced mass spectrometry-based methods to further the understanding of neuronal function, synaptic plasticity, and neurological disorders.
We will professionally help to 1) design the project; 2) prepare the samples; 3) adapt, develop and optimize mass spectrometry-based methods; 4) acquire LC-MS/MS data; 5) perform data and statistical analysis.
Services we provide
- Analyte extraction and protein proteolysis
- Label free quantitative proteomics
- Multiplexed quantitative proteomics (TMT, SILAC)
- Intact protein / antibody characterization
- PTM & chemical modification characterization
- Small molecule HRMS analysis
- Global metabolomics Analysis
- Global lipidomiccs Analysis
- Targeted metabolomics/lipidomics analysis
Equipment
- Orbitrap Fusion Lumos Tribrid mass spectrometry equipped with EASY-nLC and Vanquish Flex UHPLC.
- Orbitrap Ascend Tribrid mass spectrometry equipped with Vanquish Neo UHPLC.