Stars by the Pocketful

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ACS Central Science. 2025 Jul;. doi: 10.1021/acscentsci.5c00223

Stars by the Pocketful Lavis Lab

Lavis L, Lavis C

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Abstract

Fluorescence is magical. Shine one color of light on a fluorophore and it glows in another color. This property allows imaging of biological systems with high sensitivity─we can visualize individual fluorescent molecules in an ocean of nonfluorescent ones.

Fluorescence microscopy has long been used to study isolated cells, both living and dead, but the development of newer, tailored fluorophores is swiftly expanding the use of fluorescence imaging to more complicated systems such as intact animals. In the latest in a long string of transformative work, Sletten and co-workers introduce dyes shrouded with multiple polymer chains─effectively star polymers with a bright fluorophore at the center.

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Stars by the Pocketful

Abstract

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