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Automatic image analysis for gene expression patterns of fly embryos.

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BMC Cell Biology. 2007 Jul 10;8(Supplement 1):S7. doi: 10.1007/s12021-010-9090-x
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Automatic image analysis for gene expression patterns of fly embryos.
Peng H, Long F, Zhou J, Leung G, Eisen MB, Myers EW
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Abstract

Staining the mRNA of a gene via in situ hybridization (ISH) during the development of a D. melanogaster embryo delivers the detailed spatio-temporal pattern of expression of the gene. Many biological problems such as the detection of co-expressed genes, co-regulated genes, and transcription factor binding motifs rely heavily on the analyses of these image patterns. The increasing availability of ISH image data motivates the development of automated computational approaches to the analysis of gene expression patterns.

PMID: 17634097 [PubMed - indexed for MEDLINE]

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