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Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2021
Caveney NA, Workman SD, Yan R, Atkinson CE, Yu Z, Strynadka NCJ.
2021. CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution.. Nature Communications. 12(1):2775.
Fukudome A, Singh J, Mishra V, Reddem E, Martinez-Marquez F, Wenzel S, Yan R, Shiozaki M, Yu Z, Wang JChe-Yen et al..
2021. Structure and RNA template requirements of RNA-DEPENDENT RNA POLYMERASE 2.. Proceedings of the National Academy of Sciences of the U.S.A.. 118(51)
2022
Shaban NM, Yan R, Shi K, Moraes SN, Cheng AZ, Carpenter MA, McLellan JS, Yu Z, Harris RS.
2022. Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.. Science Advances. 8(17):eabm2827.
Hirano S, Kappel K, Altae-Tran H, Faure G, Wilkinson ME, Kannan S, F Demircioglu E, Yan R, Shiozaki M, Yu Z et al..
2022. Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA.. Nature. 610(7932):575-581.
2023
Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Yu Z, Lishko PV et al..
2023. In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes.. Nature Structural & Molecular Biology. 30(3):360-9.
2024
Zhou H, Hutchings J, Shiozaki M, Zhao X, Doolittle LK, Yang S, Yan R, Jean N, Riggi M, Yu Z et al..
2024. Quantitative Spatial Analysis of Chromatin Biomolecular Condensates using Cryo-Electron Tomography. bioRxiv.