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janelia7_blocks-janelia7_biblio_header | block
Annual Review Neuroscience. 2022 Jul 08;45:131-150. doi: 10.1146/annurev-neuro-110520-030031
Melding Synthetic Molecules and Genetically Encoded Proteins to Forge New Tools for Neuroscience. Lavis Lab
Kumar P, Lavis LD
janelia7_blocks-janelia7_biblio_abstract | block
Abstract
Unraveling the complexity of the brain requires sophisticated methods to probe and perturb neurobiological processes with high spatiotemporal control. The field of chemical biology has produced general strategies to combine the molecular specificity of small-molecule tools with the cellular specificity of genetically encoded reagents. Here, we survey the application, refinement, and extension of these hybrid small-molecule:protein methods to problems in neuroscience, which yields powerful reagents to precisely measure and manipulate neural systems.
PMID: 35226826 [PubMed - indexed for MEDLINE]
janelia7_blocks-janelia7_biblio_authors | block
Janelia Authors
Pratik Kumar
janelia7_blocks-janelia7_biblio_tools | block