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Chad Hobson

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People / Chad HobsonIntegrative Imaging
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Application Scientist
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Biography

Chad joined the Advanced Imaging Center (AIC) in 2021 as a recent PhD graduate from the department of physics and astronomy the University of North Carolina at Chapel Hill. His PhD research in Rich Superfine's lab focused on combining atomic force microscopy and single-objective light-sheet microscopy to study the mechanical properties of cell nuclei. At the AIC, Chad works primarily on the various light-sheet microscopy systems, assisting visitors from consultation to publication. Prior to graduate school, Chad received his BS in both physics and mathematics at the University of Lynchburg, where he developed models of the Tour de France and soccer ball aerodynamics.

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Education

MS/PhD, Physics and Astronomy, The University of North Carolina at Chapel Hill
BS, Physics and mathematics, University of Lynchburg
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Featured Publications

Shah, P., Hobson, C. M., et al. (2021). Nuclear Deformation Causes DNA Damage by Increasing Replication Stress. Curr. Biol. doi:10.1016/j.cub.2020.11.037.
Hobson, C. M., et al. (2020). Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics. Mol. Biol. Cell. doi:10.1091/mbc.E20-01-0073.
Hobson, C. M., et al. (2020). Combined Selective Plane Illumination Microscopy and FRAP Maps Intranuclear Diffusion of NLS-GFP. Biophys. J. doi:10.1016/j.bpj.2020.07.001.
Hobson, C. M., and Stephens, A. D. (2020). Modeling of Cell Nuclear Mechanics: Classes, Components, and Applications. Cells. doi:10.3390/cells9071623.
Nelsen, E., Hobson, C. M., et al. (2020). Combined Atomic Force Microscope and Volumetric Light Sheet System for Correlative Force and Fluorescence Mechanobiology Studies. Sci. Rep. doi:10.1038/s41598-020-65205-8.
Liu*, B., Hobson*, C. M. et al. (2019). VIEW-MOD: a versatile illumination engine with a modular optical design for fluorescence microscopy. Opt. Express. doi:10.1364/oe.27.019950.