Main Menu (Mobile)- Block

Main Menu - Block

Juvenile hormone is required to couple imaginal disc formation with nutrition in insects.

Our Research / Publications
janelia7_blocks-janelia7_biblio_header | block
Science . 2006 Jun 2;312(5778):1385-8. doi: 10.1126/science.1123652
View Article on
Juvenile hormone is required to couple imaginal disc formation with nutrition in insects. Truman LabRiddiford Lab
Truman JW, Hiruma K, Allee JP, Macwhinnie SG, Champlin DT, Riddiford LM
Note: Research in this publication was not performed at Janelia.
janelia7_blocks-janelia7_biblio_abstract | block

Abstract

In starved larvae of the tobacco hornworm moth Manduca sexta, larval and imaginal tissues stop growing, the former because they lack nutrient-dependent signals but the latter because of suppression by juvenile hormone. Without juvenile hormone, imaginal discs form and grow despite severe starvation. This hormone inhibits the intrinsic signaling needed for disc morphogenesis and does so independently of ecdysteroid action. Starvation and juvenile hormone treatments allowed the separation of intrinsic and nutrient-dependent aspects of disc growth and showed that both aspects must occur during the early phases of disc morphogenesis to ensure normal growth leading to typical-sized adults.

PMID: 16741122 [PubMed - indexed for MEDLINE]

node:body | entity_field
janelia7_blocks-janelia7_biblio_tools | block