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janelia7_blocks-janelia7_biblio_header | block
The Journal of Biological Chemistry. 2013 Jul 12;288(28):20361-8. doi: 10.1074/jbc.R113.452094
mRNA on the move: the road to its biological destiny. Singer Lab
Eliscovich C, Buxbaum AR, Katz ZB, Singer RH
Note: Research in this publication was not performed at Janelia.
janelia7_blocks-janelia7_biblio_abstract | block
Abstract
Cells have evolved to regulate the asymmetric distribution of specific mRNA targets to institute spatial and temporal control over gene expression. Over the last few decades, evidence has mounted as to the importance of localization elements in the mRNA sequence and their respective RNA-binding proteins. Live imaging methodologies have shown mechanistic details of this phenomenon. In this minireview, we focus on the advanced biochemical and cell imaging techniques used to tweeze out the finer aspects of mechanisms of mRNA movement.
PMID: 23720759 [PubMed - indexed for MEDLINE]
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janelia7_blocks-janelia7_biblio_authors | block
Janelia Authors
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