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Author Title Type [ Year(Asc)]
Filters: Author is Sawaya, Michael R  [Clear All Filters]
2024
Hou K, Ge P, Sawaya MR, Dolinsky JL, Yang Y, Jiang YXiao, Lutter L, Boyer D, Cheng X, Pi J et al..  2024.  How short peptides can disassemble ultra‐stable tau fibrils extracted from Alzheimer’s disease brain by a strain‐relief mechanismAbstractBackgroundMethodResultConclusion. Alzheimer's & Dementia. 20(S6)
2018
Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Z Zhou H, Eisenberg DS.  2018.  Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.. Nature Structural & Molecular Biology.
Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee C-T, Novikova IV, Goldschmidt L, McFarlane HT et al..  2018.  Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.. Nature Structural & Molecular Biology.
2017
Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S et al..  2017.  Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.. eLife. 6
M de la Cruz J, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SKyung et al..  2017.  Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.. Nature Methods. 14(4):399-402.
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J et al..  2017.  Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design.. The Journal of Biological Chemistry. 293(8):2888-902.
Hughes MP, Sawaya MR, Goldschmidt L, Rodriguez JA, Cascio D, Gonen T, Eisenberg DS.  2017.  Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets.. bioRxiv.
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS.  2017.  Structure-based inhibitors of tau aggregation.. Nature Chemistry.
2016
Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS.  2016.  Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.. Proceedings of the National Academy of Sciences of the United States of America. 113(40):11232-6.
2015
Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M et al..  2015.  Structure of the toxic core of α-synuclein from invisible crystals.. Nature. 525(7570):486-90.
2012
King NP, Sheffler W, Sawaya MR, Vollmar BS, Sumida JP, André I, Gonen T, Yeates TO, Baker D.  2012.  Computational design of self-assembling protein nanomaterials with atomic level accuracy.. Science. 336(6085):1171-4.