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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.
2014. 3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Lavis LD, Raines RT.
2014. Bright building blocks for chemical biology.. ACS Chemical Biology. 9(4):855-66.
Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, R Johnson J.
2014. Distinct substrate selectivity of a metabolic hydrolase from Mycobacterium tuberculosis.. Biochemistry. 53(47):7386-95.
Mast JD, De Moraes CM, Alborn HT, Lavis LD, Stern DL.
2014. Evolved differences in larval social behavior mediated by novel pheromones.. eLife. 3
Haga-Yamanaka S, Ma L, He J, Qiu Q, Lavis LD, Looger LL, C Yu R.
2014. Integrated action of pheromone signals in promoting courtship behavior in male mice.. eLife. 3:e03025.
Höckendorf B, Lavis LD, Keller PJ.
2014. Making biology transparent.. Nature Biotechnology. 32(11):1104-5.
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.
2014. Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..
2015. A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Liu Z, Lavis LD, Betzig E.
2015. Imaging live-cell dynamics and structure at the single-molecule level.. Molecular Cell. 58(4):644-59.
Lester HA, Lavis LD, Dougherty DA.
2015. Ketamine Inside Neurons? American Journal of Psychiatry. 172(11):1064-6.
R. Johnson J, Hoops GC, Savas CJ, Kartje Z, Lavis LD.
2015. A sensitive and robust enzyme kinetic experiment using microplates and fluorogenic ester substrates. Journal of Chemical Education. 92(2):385-8.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.
2015. Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2016
Lavis LD, Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z et al..
2016. Bright photoactivatable fluorophores for single-molecule imaging.. Nature Methods. 13(12):985-8.
Heckman LM, Grimm JB, Schreiter ER, Kim C, Verdecia MA, Shields BC, Lavis LD.
2016. Design and synthesis of a calcium-sensitive photocage.. Angewandte Chemie (International ed. in English).
MacDonald MJ, Lavis LD, Hilvert D, Gellman SH.
2016. Evaluation of the Ser-His dipeptide, a putative catalyst of amide and ester hydrolysis.. Organic Letters.
Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.
2016. Glutamate-induced RNA localization and translation in neurons.. Proceedings of the National Academy of Sciences of the United States of America.
Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.
2016. High-density three-dimensional localization microscopy across large volumes.. Nature Methods.
Zhen CYu, Tatavosian R, Huynh TNgoc, Duc HNguyen, Das R, Kokotovic M, Grimm JB, Lavis LD, Lee J, Mejia FJ et al..
2016. Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.. eLife. 5
Economo MN, Clack NG, Lavis LD, Gerfen CR, Svoboda K, Myers EW, Chandrashekar J.
2016. A platform for brain-wide imaging and reconstruction of individual neurons.. eLife. 5
Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG et al..
2016. Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.. Genes and Development. 30:2106-18.
Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.
2016. Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.. eLife. 5
Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL.
2016. Real-time quantification of single RNA translation dynamics in living cells.. Science. 352(6292):1425-9.
Cho W-K, Jayanth N, English BP, Inoue T, J Andrews O, Conway W, Grimm JB, Spille J-H, Lavis LD, Lionnet T et al..
2016. RNA Polymerase II cluster dynamics predict mRNA output in living cells.. eLife. 5