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Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
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Duan J, Li J, Chen G-L, Zeng B, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J et al..
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Qiu B, Matthies D, Fortea E, Yu Z, Boudker O.
2021. Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.. Sciences Advances. 7(10)
Egri SB, Ouch C, Chou H-T, Yu Z, Song K, Xu C, Shen K.
2022. Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.. Molecular Cell. 36(1)
Brouns SJJ, Turnbull AP, Willemen HLDM, Akerboom J, van der Oost J.
2007. Crystal structure and biochemical properties of the D-arabinose dehydrogenase from Sulfolobus solfataricus.. Journal of Molecular Biology. 371(5):1249-60.
Zheng H, Wisedchaisri G, Gonen T.
2013. Crystal structure of a nitrate/nitrite exchanger.. Nature. 497(7451):647-51.
Lei H-T, Ma J, Martinez SSanchez, Gonen T.
2018. Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state.. Nature Structural & Molecular Biology. 25(6):522-527.
Meng Z, Lou Z, Liu Z, Li M, Zhao X, Bartlam M, Rao Z.
2006. Crystal structure of human pyrroline-5-carboxylate reductase.. Journal of Molecular Biology. 359(5):1364-77.
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2003. Crystal structure of Pyrococcus furiosus phosphoglucose isomerase. Implications for substrate binding and catalysis.. The Journal of Biological Chemistry. 278(35):33290-7.
Schreiter ER, Sintchak MD, Guo Y, Chivers PT, Sauer RT, Drennan CL.
2003. Crystal structure of the nickel-responsive transcription factor NikR.. Nature Structural Biology. 10(10):794-9.
Akerboom J, Rivera JDVélez, Guilbe MMRodrígu, Malavé ECAlfaro, Hernandez HH, Tian L, S Hires A, Marvin JS, Looger LL, Schreiter ER.
2009. Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design.. The Journal of Biological Chemistry. 284:6455-64.
Alfaro E, Sosa LDel Valle, Sanoguet Z, Pastrana-Ríos B, Schreiter ER.
2008. Crystallization and preliminary X-ray characterization of full-length Chlamydomonas reinhardtii centrin.. Acta Crystallographica Section F Structural Biology and Crystallization Communications. 64(Pt 5):402-4.
Guilbe MMRodrígu, Malavé ECAlfaro, Akerboom J, Marvin JS, Looger LL, Schreiter ER.
2008. Crystallization and preliminary x-ray characterization of the genetically encoded fluorescent calcium indicator protein GCaMP2.. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64:629-31.
Wang Z, Wang W, Liu S, Yang F, Liu X, Hua S, Zhu L, Xu A, Hill DL, Wang D et al..
2024. CSPP1 stabilizes microtubules by capping both plus and minus ends.. Journal of Molecular Cell Biology.
Rohou A, Grigorieff N.
2015. CTFFIND4: Fast and accurate defocus estimation from electron micrographs.. Journal of Structural Biology. 192(2):216-21.
Cardona A, Tomancak P.
2012. Current challenges in open-source bioimage informatics.. Nature Methods. 9(7):661-5.
Colpitts SL, Stoklasek TA, Plumlee CR, Obar JJ, Guo C, cois LLefran\c.
2012. Cutting edge: the role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo.. Journal of Immunology. 188(6):2483-7.
Eddy SR.
2012. The C-value paradox, junk DNA and ENCODE.. Current Biology. 22(21):R898-9.
Lee K-Y, Green RA, Gutierrez E, J Gomez-Cavazos S, Kolotuev I, Wang S, Desai A, Groisman A, Oegema K.
2018. CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. eLife. 7:e36919.
Schaefer K, Xie FLiangqi, Weis-Garcia F, White N.
2020. A cytometry-based assay to determine optimal Janelia Fluor dye labelling of Halo and SNAP tags.. Journal of Biomolecular Techniques. 31(Suppl):S26.
Li S, Hsu DDF, Li B, Luo X, Alderson N, Qiao L, Ma L, Zhu HH, He Z, Suino-Powell K et al..
2014. Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis.. Cell Metab. 20(2):320-32.
Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM et al..
2017. Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation.. Science Advances. 3(6):e1603032.
Colin-York H, Li D, Korobchevskaya K, Chang VT, Betzig E, Eggeling C, Fritzsche M.
2019. Cytoskeletal actin patterns shape mast cell activation.. Communications Biology. 2:93.
Colin-York H, Javanmardi Y, Skamrahl M, Kumari S, Chang VT, Khuon S, Taylor A, Chew T-L, Betzig E, Moeendarbary E et al..
2019. Cytoskeletal control of antigen-dependent T cell activation.. Cell Reports. 26(12):3369-3379.e5.
R Johnson J, Chao T-Y, Lavis LD, Raines RT.
2007. Cytotoxic ribonucleases: the dichotomy of Coulombic forces.. Biochemistry. 46(36):10308-16.