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Biology and Engineering of the Cell Surface

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Biology and Engineering of the Cell Surface

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October 5 - 8, 2025
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Cell surface serves as a hub for protein-small molecule, protein-protein, and cell-cell interactions, actively studied across diverse fields, including developmental biology, neuroscience, physiology, cancer biology, and immunology. Complex molecular communication between cells is established and regulated by various cell surface molecules. Decades of structural, biochemical, genetic, and cellular research have provided fundamental insights into many of these molecules and their interactions. Recent breakthroughs in chemical biology, protein engineering, advanced imaging, and systems biology have driven the development of powerful new tools for precise understanding and manipulation of cell surface molecules. To bridge these two traditionally distinct fields and connect tool developers with biologists, we are convening leading scientists who employ diverse, cross-disciplinary approaches to uncover the intricate mechanisms of the cell surface.

Janelia will cover lodging and meals for all participants, and travel support is available to those in need (please indicate need in that portion of the application). Participants are expected to stay for the duration of the meeting.

The meeting will begin at 6pm ET on the first day and end by 1pm ET on the last.

Application deadline: May 20, 2025 (11:59pm ET)


Please note: Because Janelia conferences are intentionally small and selective, we may not be able to accommodate all applicants. We strive for a broad representation across labs and therefore may limit participation to one person per group. Preference is given to applicants who are active researchers in the field and intend to present their work as a poster or selected talk.


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Organizers

Jiefu Li, HHMI/Janelia Research Campus
Xinbo Yang, Sloan Kettering Institute
Xin Zhou, Dana-Farber Cancer Institute/Harvard

Invited Participants

Demet Araç-Özkan, University of Chicago
Fei Chen, Broad Institute of MIT and Harvard
Jue Chen, HHMI/Rockefeller University
Xinzhong Dong, HHMI/Johns Hopkins University
Stephen Elledge, HHMI/Harvard University
Ryan Flynn, Harvard University
Michael Funk, AAAS/Science
Chris Garcia, HHMI/Stanford University
Jay Groves, University of California, Berkeley
Shuo Han, Shanghai Institute of Biochemistry and Cell Biology
Morgan Huse, Sloan Kettering Institute
Lily Jan, HHMI/University of California, San Francisco
Natalia Jura, University of California, San Francisco
Laura Kiessling, Massachusetts Institute of Technology
Andrew Kruse, Harvard University
Yulong Li, Peking University
Liqun Luo, HHMI/Stanford University
Kayvon Pedram, HHMI/Janelia Research Campus
John Pham, Cell Press
Carol Robinson, Oxford University
Bryan Roth, University of North Carolina Chapel Hill
Alice Ting, Stanford University
Gabriel Victora, HHMI/Rockefeller University
Shaohe Wang, HHMI/Janelia Research Campus
Wenjing Wang, University of Michigan
Jim Wells, University of California, San Francisco
Peng Wu, Scripps Research
Kai Wucherpfennig, Dana-Farber Cancer Institute/Harvard
Jennifer Zallen, HHMI/Sloan Kettering Institute